IgM nephropathy presenting as full blown crescentic glomerulonephritis: first report in the literature.

DISCUSSION To our knowledge, this is the irst case of IgMN in literature presenting with full-blown CresGN. The latter has varied from 2% to 18.5%. We have earlier reported a prevalence of IgMN of 18.5% in native renal biopsies in children presenting with INS in Pakistan. The disease is deined by its immunopathologic features: the light microscopic (LM) features being highly variable ranging from minimal change lesion to variable degrees of mesangial proliferation to focal segmental glomerulosclerosis (FSGS). A few studies have also noted small subcapsular crescents in cases of IgMN. However, up till now, no case of IgMN has been reported presenting with crescentic GN (CresGN). We herein report a case of an 11-year-old child presenting clinically with rapidly progressive glomerulonephritis (RPGN) and the biopsy features of CresGN.